missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. 18797136

Tocris Bioscience™ FMF-04-159-2
GREENER_CHOICE

Artikelnummer. 18797136
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde
18797136 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 18797136 Leverandør Tocris Bioscience™ Leverandørnr. 7158/10

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members

FMF-04-159-2 is a potent inhibitor of CDK14 and CDK16 (IC50 = 40 nM for CDK14 in cellular BRET assay; IC50 values are 88 and 10 nM for CDK14 and CDK16 in kinase activity inhibition assay, respectively). Inhibits other TAIRE kinase family members at 1 μM (CDK17 and CDK18). Also binds CDK2 (IC50 = 256 nM). Displays covalent binding of CDK14, with binding sustained after washout. Causes cell cycle arrest at G2/M in cancer cell lines. Reversible control FMF-04-159-R (Cat. No. 7159) also available.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale N-[1-[[3-[[(2 E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1 H-pyrazole-3-carboxamide
CAS 2364489-81-4
Mængde 10 mg
Mål Cyclin-dependent Kinase Inhibitors
Molekylær formel C28H30Cl3N7O5S
Renhed 0.98
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.