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Tocris Bioscience™ FK 506

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:
10mg
Beskrivelse
FK 506 is a potent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC50 = 3 nM). Inhibits secretion of IL-1, IL-2 (IC50 = 1 nM), IL-3, IL-4, IL-6 (IC50 = 35 nM), GM-CSF, TNFα (IC50 = 10 nM), IFNγ and Myc from activated T cells in vitro. Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo. Identified as targeting human host cell proteins that interact with SARS-CoV-2.
Analog also available.
Tekniske data
Tekniske data
| Mængde | 10 mg |
| Produkttype | FK 506 |
| Renhed | >99% |
| Molekylvægt (g/mol) | 804.02 |
| Inhibitorer | FK 506 |
For Research Use Only
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