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Fibrin beta-chain Antibody (8E5), Alexa Fluor™ 750, Novus Biologicals™

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0.1 mL
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18310530 0.1 mL
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Artikelnummer. 18310530 Leverandør Novus Biologicals Leverandørnr. NBP281110AF750

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Beskrivelse

Mouse Monoclonal Antibody

Fibrin beta-chain Monoclonal specifically detects Fibrin beta-chain in Human samples. It is validated for ELISA.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Fibrin beta-chain
Applikationer ELISA
Klassifikation Monoclonal
Klon 800000
Konjugeret Alexa Fluor 750
Fortynding ELISA
Formulering 50mM Sodium Borate
Gene Alias Beta-Fibrinogen, epididymis secretory sperm binding protein Li 78p, fibrinogen beta chain, fibrinogen, B beta polypeptide, HEL-S-78p
Gensymboler FGB
Værtsarter Mouse
Immunogen 8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
Oprensningsmetode Protein A purified
Mængde 0.1 mL
Regulatorisk status RUO
Forskningsdisciplin Cell Cycle and Replication
Primær eller sekundær Primary
Gen-id (Entrez) 2244
Testspecificitet 8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.
Målarter Human
Indhold og opbevaring Store at 4°C in the dark.
Form Purified
Isotype IgG1 κ
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