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Fibrin beta-chain Antibody (8E5), Alexa Fluor™ 750, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-81110AF750

Additional Details : Weight : 0.00970kg

Product Code. 18310530

  • 4529.04 DKK / 0.10mL
Estimated Shipment: 28-06-2024
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Description

Description

Fibrin beta-chain Monoclonal specifically detects Fibrin beta-chain in Human samples. It is validated for ELISA.
Specifications

Specifications

Fibrin beta-chain
Monoclonal
Alexa Fluor 750
50mM Sodium Borate
FGB
8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).
0.1 mL
Cell Cycle and Replication
2244
Human
Purified
ELISA
800000
ELISA
Beta-Fibrinogen, epididymis secretory sperm binding protein Li 78p, fibrinogen beta chain, fibrinogen, B beta polypeptide, HEL-S-78p
Mouse
Protein A purified
RUO
Primary
8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.
Store at 4°C in the dark.
IgG1 κ
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