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Tocris™ Famotidine
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Artikelnummer. 18756336
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Mængde:
100 mg
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Artikelnummer. Mængde
18756336 100 mg
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Artikelnummer. 18756336 Leverandør Tocris™ Leverandørnr. 7290/100

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Potent and high affinity H2 biased inverse agonist

Famotidine is a potent and high affinity histamine H2 receptor biased inverse agonist (Kd = 14 nM, IC50 = 33 nM). Reduces basal receptor activity by 75%. Inhibits Gs-mediated pathways but acts as a partial agonist of β-arrestin recruitment (EC50 = 105 nM). Inhibits gastric acid secretion and histamine-induced mast cell activation. Also inhibits HIV replication in vitro.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
CAS 76824-35-6
Mængde 100 mg
Mål Histamine H2 Receptor Antagonists
Molekylær formel C8H15N7O2S3
Renhed 0.98
Produkttitel
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