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Invitrogen™ Factor X/Xa Polyclonal Antibody
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Artikelnummer. 16668884
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100 μL
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16668884 100 μL
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Artikelnummer. 16668884 Leverandør Invitrogen™ Leverandørnr. PA5102412

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Beskrivelse

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Factor X.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Factor X/Xa
Applikationer Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene F10
Genadgangsnr. O88947, P00742, Q63207
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymboler F10
Værtsarter Rabbit
Immunogen A synthesized peptide derived from human F10(Accession P00742), corresponding to amino acid residues A444-K488.
Oprensningsmetode Affinity chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 14058, 2159, 29243
Målarter Human, Mouse, Rat
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG
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