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Invitrogen™ Factor X Polyclonal Antibody
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Artikelnummer. 30535712
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100 μg
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30535712 100 μg
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Artikelnummer. 30535712 Leverandør Invitrogen™ Leverandørnr. PA5148470

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Beskrivelse

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Factor X
Applikationer Immunoprecipitation, Western Blot
Klassifikation Polyclonal
Koncentration 0.2 mg/mL
Konjugeret Unconjugated
Formulering PBS with trehalose and no preservative
Gene F10
Genadgangsnr. P00742
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor 10; Factor X heavy chain; Factor X light chain; factor Xa; Factor10; FX; FXA; prothrombinase; RP11-98F14.9; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymboler F10
Værtsarter Goat
Immunogen S. frugiperda insect cell line Sf 21-derived recombinant human Coagulation Factor X, Leu24-Lys488.
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 2159
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Lyophilized
Isotype IgG
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