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Invitrogen™ Factor X/Xa Monoclonal Antibody (9050)
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Artikelnummer. 11529882
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Mængde:
100 μg
Pakningsstørrelse:
100µg
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11529882 100 μg 100µg
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Artikelnummer. 11529882 Leverandør Invitrogen™ Leverandørnr. MA143035

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Beskrivelse

Rat Monoclonal Antibody

This antibody detects mouse factor X (heavy chain) and mouse factor Xa (heavy chain) by ELISA and Western blot, and cross-reacts with human factor X/Xa (Western blot only). Western blot can be performed under reducing and non-reducing conditions. Inhibitory properties: Does not inhibit PT (mouse plasma). Purity >95% by SDS-PAGE.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Factor X/Xa
Applikationer ELISA, Western Blot
Klassifikation Monoclonal
Klon 9050
Koncentration 8 mg/mL
Konjugeret Unconjugated
Formulering 50% water with 50% glycerol and no preservative
Gene F10
Genadgangsnr. O88947, P00742
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymboler F10
Værtsarter Rat
Immunogen Purified mouse factor X.
Oprensningsmetode SDS-PAGE
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 14058, 2159
Målarter Human, Mouse
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Produkttype Antibody
Form Liquid
Isotype IgG
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