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Tocris Bioscience™ Ex 26
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Artikelnummer. 18749947
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50 mg
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18749947 10 mg
18707958 50 mg
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Artikelnummer. 18749947 Leverandør Tocris Bioscience™ Leverandørnr. 5833/50

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Beskrivelse

Potent and selective S1P1 receptor antagonist

Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM). Exhibits > 3,000-fold selectivity for S1P1 over S1P2, S1P3, S1P4 and S1P5. Induces lymphocyte sequestration in peripheral lymph nodes and upregulates S1P1 receptor expression. Reduces disease severity in mice with EAE. Increases IFN-α production in stimulated dendritic cells in vivo.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid
CAS 144678-63-7
Mængde 10 mg
Opløselighed Soluble to 100mM in DMSO and to 100mM in ethanol
Molekylær formel C28H28ClFN2O3
Formel vægt 494.98
Fysisk form Solid
Farve White
Produkttype Bioactive Small Molecule
Renhed >98%

For Research Use Only.

Produkttitel
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