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Tocris Bioscience™ ET 18-OCH3

Artikelnummer. 18074992
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Mængde:
10 mg
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Artikelnummer. Mængde
18074992 10 mg
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Artikelnummer. 18074992 Leverandør Tocris Bioscience™ Leverandørnr. 7462/10

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Beskrivelse

Selective PI-PLC inhibitor, also PAF receptor agonist

ET 18-OCH3 is a synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50 = 9.6 μM in fibroblasts and adenocarcinoma cells). ET 18-OCH3 acts as an agonist at platelet-activating factor (PAF) receptors. ET 18-OCH3 is an antitumor lipid that selectively induces apoptosis in tumor cells, sparing normal cells, and activates the intracellular Fas/CD95 death receptor. ETH 18-OCH3 also triggers eryptosis and interacts with mitochondrial membranes to increase mitochondrial membrane permeability, leading to dysfunction and apoptosis. Racemic mixture.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide
CAS 70641-51-9
Mængde 10 mg
Mål Phospholipase C Inhibitors
Molekylær formel C27H58NO6P
Produkttitel
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