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Beskrivelse
Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation.
- The major estrogen secreted by the premenopausal ovary.
- Exposure to estradiol increases breast cancer incidence and proliferation.
Tekniske data
Tekniske data
| CAS | 50-28-2 |
| Smeltepunkt | 173°C to 179°C |
| Molekylær formel | C18H24O2 |
| Mængde | 250 mg |
| Synonym | estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin |
| Opløselighedsinformation | Almost insoluble in water (50mg/mL; clear, colorless solution). Freely soluble in alcohol; soluble in acetone, dioxane, other organic solvents; solutions of fixed alkali hydroxides; sparingly soluble in vegetable oils; soluble in methanol:CHCl3 (1:1). |
| InChI nøgle | VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| Optisk rotation | +76.8 (Concentration = 1, Solvent = Dioxane) (Lit.) |
| SMIL | CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O |
| IUPAC navn | (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3,17-diol |
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