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Beskrivelse
ERK5-IN-1 is a potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.
Greener Choice-anprisninger
- undefined
- Ozone-Safe or Safe for the Ozone Layer

Tekniske data
Tekniske data
Renhed | >98% |
Oversigt | ERK5-IN-1 |
Molekylvægt (g/mol) | 638.8 |
Produkttype | ERK5-IN-1 |
Mængde | 10 mg |
For Research Use Only
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Produkttitel
Tocris Bioscience™ ERK5-IN-1 >
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