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ErbB4 (HER4)
ErbB4 (HER4)
Brand: Invitrogen PV3626
Additional Details : Weight : 0.05250kg
Description
Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3. ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.Specifications
| NP_005226 | |
| Oncology and Genetic Disease Research, Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| 61.6kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| ErbB4 (HER4) | |
| ERBB4 was pre-diluted in enzyme dilution buffer and assayed in 12.5mM Tris (pH 7.5), 10 MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Amino acids 708-993 | |
| 550nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 85% by SDS-PAGE |
| 0.34mg/mL | |
| 2066 | |
| ERBB4 (HER4) | |
| –80°C | |
| 1 Each | |
| ErbB4 (HER4) | |
| EGF receptor (ErbB) | |
| ErbB4 (HER4) | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
For Research Use Only. Not for use in diagnostic procedures.