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STEMCELL Technologies (-)-Epigallocatechin Gallate

Artikelnummer. 17170252
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Mængde:
100 mg
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Artikelnummer. Mængde
17170252 100 mg
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Artikelnummer. 17170252 Leverandør STEMCELL Technologies Leverandørnr. 73644

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Beskrivelse

Antioxidant and epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)

  • (-)-Epigallocatechin Gallate is the most abundant polyphenol catechin antioxidant present in green tea (Frémont et al.; Johnson & Maddipati; Miller & Rice-Evans) and is known to inhibit DNA methyltransferases (DNMTs; IC50 = 0.21 - 0.47 μM; Lee et al.) (-)-Epigallocatechin Gallate also inhibits the formation of oxidized low-density lipoproteins (Yoshida et al.), which have a pathological role in cardiovascular diseases and atherosclerosis (Itabe et al.) (-)-Epigallocatechin Gallate has also been shown to inhibit peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine (Fiala et al.)

Tekniske data

CAS 989-51-5
Synonym EGCG; NVP-XAA723; Tea catechin
Mængde 100 mg
Molekylær formel C22H18O11
Renhed ≥98%
Produkttitel
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