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Epiberberine chloride, MedChemExpress

Artikelnummer. 16411348
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16411348 5 mg
16408908 10 mg
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Artikelnummer. 16411348 Leverandør Medchem Express Leverandørnr. HYN0226A

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Beskrivelse

MedChemExpress Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively.

Epiberberine chloride has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease. Epiberberine chloride inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways. Epiberberine has the potential effect in the research of diabetic disease.

Tekniske data

Kemisk navn eller materiale Epiberberine chloride
CAS 889665-86-5
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C20H18ClNO4
Mængde 5 mg
Opløselighedsinformation DMSO : 25 mg/mL (67.24 mM; Need ultrasonic)
SMIL COC1=C(OC)C=C2C(CC[N+]3=C2C=C(C=C4)C(C5=C4OCO5)=C3)=C1.[Cl-]
Molekylvægt (g/mol) 371.81
Formel vægt 371.81
Procent renhed 98.89%
Grad Research
Fysisk form Solid
Til brug med (applikation) Metabolism-sugar/lipid metabolism
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Research purposes only

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