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Tocris Bioscience™ Entacapone
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Artikelnummer. 30001556
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50 mg
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30001556 10 mg
30001572 50 mg
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Artikelnummer. 30001556 Leverandør Tocris Bioscience™ Leverandørnr. 4720/10

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Description

Potent COMT inhibitor; blocks α-synuclein aggregation

Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits α-synuclein aggregation in an in vitro assay; blocks α-synuclein-induced cell death in PC-12 cells.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 130929-57-6
Molekylær formel C14H15N3O5

Specifications

Kemisk navn eller materiale Entacapone
Mængde 10 mg
Formel vægt 305.29
Renhed >99%
Molekylvægt (g/mol) 305.29
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