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Embelin, MedChemExpress

Artikelnummer. 16487358
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Mængde:
10 mg
50 mg
Pakningsstørrelse:
50mg
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16487358 10 mg -
16423387 50 mg 50mg
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Artikelnummer. 16487358 Leverandør Medchem Express Leverandørnr. HY17473

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Beskrivelse

MedChemExpress Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells.

Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells.

Tekniske data

Kemisk navn eller materiale Embelin
Fysisk form Solid
CAS 550-24-3
Farve Orange
Mængde 10 mg
Renhedsgrad noter Research
Molekylær formel C17H26O4
Til brug med (applikation) Cancer-programmed cell death
Synonym Embelic acid Emberine NSC 91874
Opløselighedsinformation DMSO : ≥ 50 mg/mL (169.84 mM)
SMIL O=C1C(O)=C(CCCCCCCCCCC)C(C(O)=C1)=O
Molekylvægt (g/mol) 294.39
Formel vægt 294.39
Procent renhed 98.19%
Grad Research
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Research purposes only

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