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EGFR (ErbB1) [L858R] Recombinant Human Protein, Invitrogen™

EGFR (ErbB1) [L858R] Recombinant Human Protein

Brand:  Invitrogen PV4128

Additional Details : Weight : 0.05250kg

Product Code. 11583617

  • 4375.00 DKK / 10µg
Estimated Shipment: 18-04-2024
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Description

Description

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.
Specifications

Specifications

NP_005219.2; L858R
Cell Viability, Pharma and Biopharma, Cell Proliferation and Function, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay
90.5kDa
10μg
For research use only. Not for use in diagnostic procedures
EGFR (ErbB1) L858R
EGFR (ErbB1) L858R was pre-diluted in enzyme dilution buffer and assayed in 25mM HEPES (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]- γ-ATP for 10 minutes at 30°C
Amino acids 668-1210: L858R
840nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1μg/mL
GST Tag
Kinase and inhibitors
60% by SDS-PAGE
0.32mg/mL
1956, 7124
EGFR (ErbB1) [L858R] Recombinant Human Protein
–80°C
1 Each
EGFR (ErbB1) [L858R] Recombinant Human Protein
EGF receptor (ErbB)
EGFR (ErbB1) [L858R] Recombinant Human Protein
Human
Baculovirus
Receptor tyrosine kinases
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For Research Use Only. Not for use in diagnostic procedures.