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Tocris Bioscience™ Eeyarestatin I
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Artikelnummer. 18014892
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Mængde:
10 mg
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18014892 10 mg
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Artikelnummer. 18014892 Leverandør Tocris Bioscience™ Leverandørnr. 3922/10

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Beskrivelse

Potent inhibitor of ER-associated protein degradation and translocation

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquitinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination. Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the proapoptotic protein NOXA. Also enhances adeno-associated viral transduction in multiple cells types.
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Specifications

Kemisk navn eller materiale Eeyarestatin I
CAS 412960-54-4
Mængde 10 mg
Molekylær formel C27H25Cl2N7O7
Formel vægt 630.44
Renhed >98%
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