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STEMCELL Technologies EC23

Artikelnummer. 17140172
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Mængde:
1 mg
10 mg
Pakningsstørrelse:
1mg
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17140172 1 mg 1mg
17150172 10 mg -
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Artikelnummer. 17140172 Leverandør STEMCELL Technologies Leverandørnr. 73102

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Beskrivelse

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

  • EC23 is a retinoic acid receptor (RAR) agonist with pan-RAR activity (EC50: RARα 41 nM, RARβ 0.5 nM, RARγ 0.4 nM), while having no appreciable activity for retinoid X receptors (RXR; EC50> 10μM for all; Gambone et al.) It is a photostable synthetic analog of all-trans retinoic acid (ATRA; Christie et al. 2008)
  • EC23 also weakly activates aryl hydrocarbon receptor (Gambone et al.)
  • Induces neural differentiation of human pluripotent stem cells, similarly to ATRA (Christie et al. 2010; Clemens et al.)
  • Induces neuronal differentiation of human fetal neural progenitor cell line ReNcell 197VM (Christie et al. 2010)

Tekniske data

CAS 104561-41-3
Synonym AGN 190205; BASF 46928
Mængde 1 mg
Molekylær formel C23H24O2
Renhed ≥98%
Produkttitel
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