missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Biokemiske reagenser
  4. Lipider og lipidderivater
  5. Prenol lipider
  6. Diterpenoider
  7. Docetaxel, 99%

Docetaxel, 99%

Artikelnummer. 15452989
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
100 mg
500 mg
1 g
Pakningsstørrelse:
100mg
1g
500mg
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde Pakningsstørrelse
15452989 1 g 1g
15462989 100 mg 100mg
15472989 500 mg 500mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 15452989 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J60174.03
  • ONLINE EXCLUSIVE PRICE
    6410.54 DKK
    5767.65 DKK / 1g
    Spare 642.89 DKK
    10% Slukket
Se alle kampagner
 Begrænset vare
På lager
Læg i indkøbskurv
5449.02 DKK valid until 2026-09-25
BEDSTE tilbudspris! Brug kampagnekoden "27966" for at få din tilbudspris.
Læg i indkøbskurv
Request Bulk or Custom Format

missing translation for 'validMainframeMsg'

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Docetaxel, CAS # 114977-28-5, is a cytotoxic, semisynthetic, second-generation taxane derived from the needles of the European yew tree and displays antineoplastic, antibiotic, and antimicrotubule activities. | CAS: 114977-28-5 | C43H53NO14 | 807.89 g/mol

Docetaxel is a second-generation cytotoxic antimicrotubule agent and is mostly used in the pharmaceutical industry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Docetaxel is an analog of taxol, and is considered to be a cytotoxic, semisynthetic, second-generation taxane that exhibits antineoplastic, antibiotic, and antimicrotubule activities
• Docetaxel is capable of inhibiting cellular mitosis. This compound promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability inhibits the normal dynamic reorganization of the microtubule network that is essential for vital interphase and mitotic cellular functions. This results in the persistence of abnormal microtubule structures leading to cell-cycle arrest and cell death

Application

• Docetaxel can inhibit angiogenesis by acting on vascular endothelial growth factor (VEGF) associated with cancer cells
• This compound has been used to investigate the effect of lysosomal autophagic flux in gastric cancer cells

TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 114977-28-5
Molekylær formel C43H53NO14
Molekylvægt (g/mol) 807.89
MDL nummer MFCD00800737
InChI nøgle ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Synonym docetaxel, taxotere, docetaxel anhydrous, docetaxol, emdoc, docetaxel, trihydrate, docetaxel inn, taxotere tn, unii-699121phca, txl
PubChem CID 148124
ChEBI CHEBI:4672
SMIL CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Tekniske data

Kemisk navn eller materiale Docetaxel
Smeltepunkt 186°C to 192°C
Farve White
Mængde 1 g
Merck Index 14,3397
Opløselighedsinformation Soluble in dimethyl sulfoxide and ethanol; Insoluble in water.
Formel vægt 807.88
Procent renhed 99%
Fysisk form Powder

RUO – Research Use Only

Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.