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DMOG, MedChemExpress

Artikelnummer. 16481786
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16481786 500 mg
16452967 50 mg
16451206 200 mg
16426986 100 mg
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Artikelnummer. 16481786 Leverandør Medchem Express Leverandørnr. HY15893

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Beskrivelse

MedChemExpress DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.

Tekniske data

Kemisk navn eller materiale DMOG
CAS 89464-63-1
Farve White
Renhedsgrad noter Research
Molekylær formel C6H9NO5
Mængde 500 mg
Synonym Dimethyloxallyl Glycine
Opløselighedsinformation DMSO : ≥ 50 mg/mL (285.49 mM) ∣H2O : 50 mg/mL (285.49 mM; Need ultrasonic)
SMIL O=C(OC)CNC(C(OC)=O)=O
Molekylvægt (g/mol) 175.14
Formel vægt 175.14
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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