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Tocris Bioscience™ Dihydro-β-erythroidine hydrobromide
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Artikelnummer. 18094072
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Mængde:
10 mg
50 mg
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Artikelnummer. Mængde
18094072 50 mg
18063972 10 mg
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Artikelnummer. 18094072 Leverandør Tocris Bioscience™ Leverandørnr. 2349/50

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Beskrivelse

α4β2, muscle type and Torpedo nAChR antagonist

Dihydro-β-erythroidine hydrobromide is a member of the Erythrina alkaloids, it is a competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α4 receptor subunit (IC50 values are 0.19 and 0.37 μM for α4β4 and α4β2 receptors, respectively). Antagonizes behavioral effects of nicotine in vivo. Dihydro-β-erythroidine blocks excitation of striatal GABAergic neurons, which completely suppress polysynaptic inhibition between striatal cholinergic interneurons. Dihydro-β-erythroidine hydrobromide has antidepressive-like effects in mice (forced swim and mouse suspension). Orally bioavailable
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Kemiske identifikatorer

CAS 29734-68-7
Molekylær formel C16H22BrNO3

Tekniske data

Kemisk navn eller materiale Dihydro-β-erythroidine hydrobromide
Mængde 50 mg
Formel vægt 356.26
Renhed >98%
Molekylvægt (g/mol) 356.26
Produkttitel
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