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Di-tert-butyl N,N-diethylphosphoramidite, 94%

Artikelnummer. 11377169
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5 g
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5g
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Artikelnummer. 11377169 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. H27380.06
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Beskrivelse

CAS: 117924-33-1 | C12H28NO2P | 249.335 g/mol

A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

Solubility
Hydrolyzes in water. Soluble in chloroform and methanol.

Notes
Moisture sensitive. Store away from water/moisture, heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep it refrigerated. Keep ignition sources away.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 117924-33-1
Molekylær formel C12H28NO2P
Molekylvægt (g/mol) 249.335
MDL nummer MFCD00134307
InChI nøgle KUKSUQKELVOKBH-UHFFFAOYSA-N
Synonym di-tert-butyl n,n-diethylphosphoramidite, di-tert-butyl diethylphosphoramidite, di-t-butyl n,n-diethylphosphoramidite, phosphoramidous acid, diethyl-, bis 1,1-dimethylethyl ester, n-bis 2-methylpropan-2-yl oxy phosphanyl-n-ethylethanamine, acmc-1c42i, di-t-butyl diethylphosphoramidite, di-tert-butyl diethylamidophosphite, di-tert-butoxy diethylamino phosphine
PubChem CID 4251849
IUPAC navn N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine
SMIL CCN(CC)P(OC(C)(C)C)OC(C)(C)C

Tekniske data

Kemisk navn eller materiale Di-tert-butyl N,N-diethylphosphoramidite
Tæthed 0.896
Kogepunkt 39°C to 41°C (0.3 mmHg)
Flammepunkt 78°C (172°F)
Brydningsindeks 1.434
Mængde 5 g
Følsomhed Moisture sensitive; May form a precipitate
Opløselighedsinformation Hydrolyzes in water. Soluble in chloroform and methanol.
Formel vægt 249.33
Procent renhed 94%

RUO – Research Use Only

Produkttitel
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