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Dexamethasone, 96%, Thermo Scientific Chemicals

Catalog Number 10053130
313.00 DKK valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
250 mg
1 g
5 g
Packaging:
Glass bottle
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
50-02-2
C22H29FO5
392.47
MFCD00064136
UREBDLICKHMUKA-CXSFZGCWSA-N
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
5743
CHEBI:41879
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
50-02-2
C22H29FO5
392.47
MFCD00064136
UREBDLICKHMUKA-CXSFZGCWSA-N
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
5743
CHEBI:41879
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

TRUSTED_SUSTAINABILITY
Melting Point 255.0°C to 261.0°C
Color White
Loss on Drying 0.5% max. (105°C, 3 hrs)
Infrared Spectrum Authentic
Assay Percent Range 96%
Packaging Glass bottle
Quantity 250 mg
Merck Index 15, 2945
Specific Rotation + 75.00
Solubility Information Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform
Spectrophotometry 95% min. (on dried substance)
IUPAC Name (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Formula Weight 392.46
Percent Purity 96%
Related Substances (HPLC) Passes test
Physical Form Crystalline Powder
Chemical Name or Material Dexamethasone
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compliance-icons
Product Identifier
  • Dexamethasone
Signal Word
  • Warning
Hazard Category
  • Carcinogenicity Category 2
Hazard Statement
  • H351-Suspected of causing cancer.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only

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