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STEMCELL Technologies Dexamethasone

Artikelnummer. 17150022
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Mængde:
500 mg
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Artikelnummer. 17150022

Brand: STEMCELL Technologies 72092

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Beschreibung

Glucocorticoid pathway activator; Activates glucocorticoid receptor

  • Dexamethasone is a synthetic glucocorticoid, similar to the natural glucocorticoid hydrocortisone
  • Dexamethasone has an increased affinity for glucocorticoid receptors when compared to the natural hydrocortisone ligand (Kd = 5 nM vs 17 nM)
  • Promotes transdifferentiation of hepatocytes from mouse pancreatic cells (Shen et al.)
  • Promotes osteogenic, adipogenic, and chondrogenic differentiation of human mesenchymal cells (Jaiswal et al.), Mackay et al.), Pittenger et al.)
  • Promotes osteogenic, adipogenic, and chondrogenic differentiation of mouse mesenchymal cells (Tropel et al.)
  • Promotes differentiation of mature hepatocytes from mouse and human embryonic stem (ES) cells (Cai et al.), Kubo et al.)
  • Promotes maturation of fetal mouse hepatocytes (Kamiya et al.)

Specifications

CAS 50-02-2
Synonym MK 125; NSC 34521
Mængde 500 mg
Molekylær formel C22H29FO5
Renhed ≥98%
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