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TOKU-E™ Daptomycin ReadyMade™ Solution

Artikelnummer. 30044059
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Mængde:
10 x 0,5 ml
Pakningsstørrelse:
5ml
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30044059 10 x 0,5 ml 5ml
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Artikelnummer. 30044059 Leverandør TOKU-E™ Leverandørnr. D10810x0.5ML

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Beskrivelse

Daptomycin ReadyMade™ Solution is provided as a sterile-filtered solution in ~ 10% β-cyclodextrin saline solution.

  • CAS Number: 103060-53-3
  • Molecular Formula: C72H101N17O26
  • Molecular Weight: 1620.67 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Streptomyces roseosporus
  • Spectrum: Daptomycin targets Gram-positive organisms including GRE (glycopeptide-resistant Enterococci) and MRSA (methicillin-resistant Staphylococcus aureus)
  • Mechanism of Action: Daptomycin peptides interact with anionic phospholipids in the membrane of Gram-positive bacteria. Peptides integrate into the membrane by a calcium-mediated process and interact with membrane phospholipid head groups and acyl chains. Finally, a pore or channel is formed which can kill the cell by membrane disruption/depolarization or cellular uptake of Daptomycin leading to disruption of intracellular processes such as synthesis of DNA, RNA, and protein which results in bacterial cell death. The activity of Daptomycin is dependent on the presence of physiologic levels of free calcium ions

Tekniske data

Kemisk navn eller materiale Daptomycin
Fysisk form Liquid
CAS 103060-53-3
pH 6.5
Kilde Streptomyces roseosporus
Emballage 2 mL plastic vial
Steril filtreret Yes, 0.22 μm
Sterilitet Sterile
Farve Clear Colorless to Pale Yellow
Koncentration 1 to 1.05 mg/mL
Mængde 10 x 0,5 ml
Renhedsgrad noter >95% (HPLC)
Analyseprocentområde >95.0%
Assay Procent Noter Daptomycin, Dried Basis
Molekylær formel C72H101N17O26
Produktlinje ReadyMade™ Solutions
Forsendelsestilstand Ice Pack
Synonym LY-146032; Cubicin
IUPAC navn (3S)-3-[[(2R)-4-amino-2-[[(2S)-2-(decanoylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-oxobutanoyl]amino]-4-[[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonazacyclohentriacont-30-yl]amino]-4-oxobutanoic acid
Molekylvægt (g/mol) 1620.67 g/mol
Formel vægt 1620.67 amu
Procent renhed >95%
Grad Antibiotic
Koncentration eller sammensætning (efter analyt eller komponenter) Daptomycin: 0.1%; Sulfobutyl Ether beta;-Cyclodextrin: 5 to 50%
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