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Cyclopiazonic acid, 98%, Thermo Scientific™

Inhibitor of the sarco/endoplasmic reticulum calcium pump, calcium-ATPase

Brand:  Thermo Scientific Alfa Aesar J61594.MA

Mængde 10mg

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Regulatorisk: Dette produkt falder ind under Lov om kemiske stoffer og produkter - lovbekendtgørelse nr. 1755 af 22. december 2006. Hvis det er relevant, skal kunden fremskaffe en licens før levering.

Produktkode 15464169

  • 1716.44 DKK / 10mg

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
The use of Cyclopiazonic acid on Langendorff-perfused murine hearts displayed anti-arrhythmic effects. Also, administration of cyclopiazonic acid on rat soleus muscle showed a decrease in hormone sensitive lipase activity and triacylglycerol hydrolysis. It is also used as an inhibitor of endoplasmic reticulum Ca2+-ATPase.

Solubility
Soluble in DMSO (100 mM), ethanol (5 mM), DMF (∼20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Keep in a dry place. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

18172-33-3
336.391
SZINUGQCTHLQAZ-AFAVFJNCSA-N
54711281
C20H20N2O3
MFCD00167445
cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020
CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O

Tekniske data

Cyclopiazonic acid
C20H20N2O3
10mg
cyclopiazonic acid, alpha-cyclopiazonic acid, unii-x9tly4580z, ccris 4942, alpha-cyclopiazonate, cyclopyazonic acid, 6ar,10z,11as,11br-10-1-hydroxyethylidene-7,7-dimethyl-6a,7,11a,11b-tetrahydro-6h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indole-9,11 2h,10h-dione, 9h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-9-one, 2,6,6a,7,11a,11b-hexahydro-10-acetyl-7,7-dimethyl-11-hydroxy-, 6a-alpha,11a,11b-alpha, 6ar,11as,11br-10-acetyl-9-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-11h-pyrrolo 1',2':2,3 isoindolo 4,5,6-cd indol-11-one, ambotzls-1020
SZINUGQCTHLQAZ-AFAVFJNCSA-N
336.391
336.39
18172-33-3
MFCD00167445
UN2811
Soluble in DMSO (100 mM),ethanol (5 mM),DMF (∽20mg/ml),and 1:1 DMSO:PBS(pH 7.2) (0.5mg/ml). Insoluble in water.
CC(=O)C1=C(C2C3C(CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O
54711281
≥99%
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