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PeproTech CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Brand: PeproTech 500-P87A-100UG
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Beskrivelse
AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human SDF-1alpha (CXCL12). Anti-Human SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography employing an immobilized Human SDF-1alpha (CXCL12) matrix. Sandwich ELISA: To detect Human SDF-1alpha (CXCL12) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human SDF-1alpha (CXCL12) (500-P87ABt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human SDF-1alpha (CXCL12). Western Blot: To detect Human SDF-1alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human SDF-1alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Tekniske data
| CXCL12 alpha (SDF-1 alpha) | |
| Polyclonal | |
| Unconjugated | |
| CXCL12 | |
| 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1α; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1α; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 6387 | |
| -20°C | |
| Lyophilized |
| ELISA, Western Blot | |
| 0.1-1.0 mg/mL | |
| PBS with no preservative | |
| P48061 | |
| CXCL12 | |
| E.coli-derived Recombinant Human SDF-1alpha (CXCL12). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody |
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