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Invitrogen™ CX3CR1 Recombinant Rabbit Monoclonal Antibody (1H14L7)

Artikelnummer. 15773115 Shop alle Thermo Scientific produkter
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Mængde:
100 μg
Pakningsstørrelse:
100µg
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15773115 100 μg 100µg
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Artikelnummer. 15773115 Leverandør Invitrogen™ Leverandørnr. 702321

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Beskrivelse

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Dog, Cat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CX3CR1
Applikationer Western Blot, Immunocytochemistry
Klassifikation Recombinant Monoclonal
Klon 1H14L7
Koncentration 0.5 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.09% sodium azide; pH 7.4
Gene CX3CR1
Genadgangsnr. P35411, P49238, Q9Z0D9
Gene Alias Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28
Gensymboler CX3CR1
Værtsarter Rabbit
Immunogen Peptides corresponding to human CX3CR1 (aa6-19, 339-351).
Oprensningsmetode Protein A
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 13051, 1524, 171056
Målarter Human, Mouse, Rat
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG
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