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Invitrogen™ Cullin 5 Recombinant Rabbit Monoclonal Antibody (K01_1P96)

Beskrivelse
Cullin 5 Recombinant Monoclonal Antibody for Western Blot
CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.
Tekniske data
Tekniske data
| Antigen | Cullin 5 |
| Applikationer | Western Blot |
| Klassifikation | Recombinant Monoclonal |
| Klon | K01_1P96 |
| Koncentration | 1 mg/mL |
| Konjugeret | Unconjugated |
| Formulering | 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4 |
| Gene | CUL5 |
| Genadgangsnr. | Q93034, Q9D5V5, Q9JJ31 |
| Gene Alias | 4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; CUL5; CUL-5; cullin 5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); Vacm1; VACM-1; vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1 |
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Produkttitel
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