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CTU2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand: Invitrogen PA588908

Product Code. 16546981

4030.00 DKK / 100µL

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Description

Immunogen sequence: HVLGAGGGPG PTQGEEQPPQ PPLDPQNLAR PPAPAQTEAL SQLFCSVRTL TAKEELLQTL RTHLILHMAR AHGYSKVMTG DSCTRLAIKL MTNLALGRGA FLAWDTGFSD ERHGDVVVVR PMRDHTLKEV AFYNRLFSVP SVFTPAVDTK APEKASIHRL MEAFILRLQT QFPSTVSTVY RTSEKLVKGP RDGPAAGDSG PRCLLCMCAL DVDAADSATA FGAQTSSRLS QMQSPIPLTE TRTPPGPCCS PGVGWAQRCG QGACRREDPQ ACIEEQLCYS CRVNMKDLPS LDPLPPYILA EAQLRTQRAW GLQEIRDCLI EDSDDEAGQS; Positive Samples: A-431, Jurkat; Cellular Location: Cytoplasm

Cytoplasmic tRNA 2-thiolation protein 2 (CUT2), also named as C16orf84 or NCS2, is a 515 amino acid protein, which belongs to the CUT2 family. C16orf84 localizes in the cytoplasm and Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). C16orf84 may act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thio-carboxylated URM1 onto the uridine of tRNAs at wobble position.

Specifications

Antigen	CTU2
Classification	Polyclonal
Conjugate	Unconjugated
Gene	CTU2
Gene Alias	2310061F22Rik, C16orf84, Ctu2, Cytoplasmic tRNA 2-thiolation protein 2, cytoplasmic tRNA 2-thiolation protein 2 {ECO:0000255, cytosolic thiouridylase subunit 2, cytosolic thiouridylase subunit 2 homolog, cytosolic thiouridylase subunit 2 homolog (S. pombe), HAMAP-Rule:MF_03054}, Ncs2, UPF0432
Host Species	Rabbit
Purification Method	Affinity Chromatography
Regulatory Status	RUO
Gene ID (Entrez)	348180
Content And Storage	-20° C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	Western Blot
Concentration	1.72 mg/mL
Formulation	PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.	Q2VPK5
Gene Symbols	CTU2
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 186-515 of human CTU2 (NP_0010127771)
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG

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CTU2 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated

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CTU2 Polyclonal Antibody, Invitrogen™

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