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Invitrogen™ Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein

Recombinant Protein

4245.00 DKK - 61400.00 DKK

Specifications

Accession Number	P49674
Concentration	See Label
For Use With (Application)	Kinase Assay
Formulation	50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez)	1454

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Products 3

Product Code	Brand	Quantity	Price	Quantity & Availability
Product Code	Brand	Quantity	Price	Quantity & Availability
15960403 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A33498	10 μg	4245.00 DKK 10µg		Please sign in to purchase this item. Need a web account? Register with us today!

17118815 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A33552	100 μg	19780.00 DKK 100µg		Please sign in to purchase this item. Need a web account? Register with us today!

17138835 View Documents missing translation for 'viewProductCertificates'	Invitrogen™ A33721	1 mg	61400.00 DKK 1mg		Please sign in to purchase this item. Need a web account? Register with us today!

Description

CSNK1E serine/threonine kinase is a member of the CK1 family which plays an important role in diverse cell processes, including DNA replication and repair. CSNK1E is a regulator of Yes-associated protein (YAP) transcription coactivator, which is a key regulator of organ size and a candidate human oncogene. CSNK1E is activated by CCK2R and then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CSNK1E can phosphorylate topoisomerase (topo) II alpha at serine-1106 and this regulates the enzyme activity and sensitivity to topo II-targeted drugs.

Specifications

Accession Number	P49674
For Use With (Application)	Kinase Assay
Gene ID (Entrez)	1454
Name	Human CSNK1E (CK1 epsilon) [R178C], GST Tag
Common Name	CK1 epsilon (R178C Mutant)
Conjugate	Unconjugated
Recombinant	Recombinant
Sequence	Full length
Shipping Condition	Dry Ice
Form	Liquid

Concentration	See Label
Formulation	50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Molecular Weight (g/mol)	73.6 kDa
Gene Alias	CK1
KinaseFamily	CK1 Kinase Family
Species	Human
Protein Tag	GST-tag
Content And Storage	-80°C, Avoid Freeze/Thaw Cycles
Expression System	Insect cells

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Invitrogen™ Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein

Specifications

Description

Specifications

Documents