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Invitrogen™ Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein Product Code.: 15960403
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Invitrogen™ Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein

Product Code. p-7180961
10 μg, 10µg
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
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Product Code. 15960403

Brand: Invitrogen™ A33498

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Description

Recombinant Protein

CSNK1E serine/threonine kinase is a member of the CK1 family which plays an important role in diverse cell processes, including DNA replication and repair. CSNK1E is a regulator of Yes-associated protein (YAP) transcription coactivator, which is a key regulator of organ size and a candidate human oncogene. CSNK1E is activated by CCK2R and then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CSNK1E can phosphorylate topoisomerase (topo) II alpha at serine-1106 and this regulates the enzyme activity and sensitivity to topo II-targeted drugs.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49674
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 1454
Molecular Weight (g/mol) 73.6 kDa
Name Human CSNK1E (CK1 epsilon) [R178C], GST Tag
Quantity 10 μg
Gene Alias CK1
Common Name CK1 epsilon (R178C Mutant)
KinaseFamily CK1 Kinase Family
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Full Length, Recombinant, Mutant
Form Liquid
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Certificates

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4 results found
Lot Number Certificate Type Date Product Code
Lot Number2672105 Certificate TypeCertificate of Analysis Date25/04/2023 Product CodeA33498
Lot Number2050918 Certificate TypeCertificate of Analysis Date05/01/2019 Product CodeA33498
Lot Number1965180 Certificate TypeCertificate of Analysis Date30/04/2018 Product CodeA33498
Lot Number1861479 Certificate TypeCertificate of Analysis Date13/04/2017 Product CodeA33498
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