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Tocris Bioscience™ CP 122721 hydrochloride
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Artikelnummer. 18776489
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Mængde:
5 mg
25 mg
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18776489 25 mg
18758758 5 mg
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Artikelnummer. 18776489 Leverandør Tocris Bioscience™ Leverandørnr. 3649/25

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Beskrivelse

High affinity NK1 receptor antagonist

CP 122721 hydrochloride is a high affinity NK1 antagonist (pIC50 = 9.8). Suppresses recruitment of immunocytes in respiratory syncytial virus (RSV)-infected rats after capsaicin stimulation. Also blocks substance P-induced excitation of locus ceruleus cells in guinea pig brain slices (IC50 = 7 nM). Exhibits anxiolytic and antidepressant-like effects. Active in vivo.
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Tekniske data

CAS 145877-52-7
Synonym (2S,3S)-N-[[2-Methoxy-5-(trifluoromethoxy)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride
Mængde 25 mg
Molekylær formel C20H23F3N2O2.2HCl
Formel vægt 453.33
Renhed 98%
Produkttitel
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