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  6. ClozapineClozapine N-oxide, MedChemExpress

ClozapineClozapine N-oxide, MedChemExpress

Artikelnummer. 16493317
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Artikelnummer. 16493317 Leverandør Medchem Express Leverandørnr. HY17366

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Description

MedChemExpress Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.

Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.

Specifications

Kemisk navn eller materiale ClozapineClozapine N-oxide
Fysisk form Solid
CAS 34233-69-7
Farve Yellow
Mængde 50 mg
Renhedsgrad noter Research
Molekylær formel C18H19ClN4O
Til brug med (applikation) Neuroscience-Neuromodulation
Opløselighedsinformation DMSO : ≥ 100 mg/mL (291.70 mM) ∣H2O : 1 mg/mL (2.92 mM; Need ultrasonic)
SMIL [O-][N+]1(C)CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1
Molekylvægt (g/mol) 342.82
Formel vægt 342.82
Procent renhed 99.25%
Grad Research
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Research purposes only

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