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Clotrimazole, Thermo Scientific™

Specific inhibitor of calcium-activated potassium channels

Brand:  Thermo Scientific Alfa Aesar J63895.14

Mængde 25g

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Produktkode 15496049

  • 2492.57 DKK / 25g

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

Solubility
Soluble in chloroform, DMSO, DMF and alcohols

Notes
Store at room temperature. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

23593-75-1
344.842
VNFPBHJOKIVQEB-UHFFFAOYSA-N
2812
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
C22H17ClN2
MFCD00057220
1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
CHEBI:3764
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Tekniske data

Clotrimazole
White
C22H17ClN2
14,2417
Soluble in chloroform, DMSO, DMF and alcohols
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
344.842
CHEBI:3764
23593-75-1
25g
MFCD00057220
1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
VNFPBHJOKIVQEB-UHFFFAOYSA-N
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
2812
344.84
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