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Clotrimazole

Artikelnummer. 15496049
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5 g
25 g
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25g
5g
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Artikelnummer. 15496049 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J63895.14
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Forventet forsendelse: 07-10-2026
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Beskrivelse

Specific inhibitor of calcium-activated potassium channels | CAS: 23593-75-1 | C22H17ClN2 | 344.842 g/mol

Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

Solubility
Soluble in chloroform, DMSO, DMF and alcohols

Notes
Store at room temperature. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 23593-75-1
Molekylær formel C22H17ClN2
Molekylvægt (g/mol) 344.842
MDL nummer MFCD00057220
InChI nøgle VNFPBHJOKIVQEB-UHFFFAOYSA-N
Synonym 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
PubChem CID 2812
ChEBI CHEBI:3764
IUPAC navn 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
SMIL C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Tekniske data

Kemisk navn eller materiale Clotrimazole
Type Clotrimazole
Fysisk form Powder
Smeltepunkt 141°C to 149°C
Farve White
Mængde 25 g
Merck Index 14,2417
Opløselighedsinformation Soluble in chloroform, DMSO, DMF and alcohols
Formel vægt 344.84

RUO – Research Use Only

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