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Clotrimazole, Thermo Scientific™
Specific inhibitor of calcium-activated potassium channels
Brand: Thermo Scientific Alfa Aesar J63895.06
| Mængde | 5g |
|---|
Denne vare kan ikke returneres.
Se returpolitik
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsClotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
Solubility
Soluble in chloroform, DMSO, DMF and alcohols
Notes
Store at room temperature. Incompatible with oxidizing agents.
Kemiske identifikatorer
| 23593-75-1 | |
| 344.842 | |
| VNFPBHJOKIVQEB-UHFFFAOYSA-N | |
| 2812 | |
| 1-[(2-chlorophenyl)-diphenylmethyl]imidazole |
| C22H17ClN2 | |
| MFCD00057220 | |
| 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole | |
| CHEBI:3764 | |
| C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 |
Tekniske data
| Clotrimazole | |
| White | |
| C22H17ClN2 | |
| 14,2417 | |
| Soluble in chloroform, DMSO, DMF and alcohols | |
| C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 | |
| 344.842 | |
| CHEBI:3764 |
| 23593-75-1 | |
| 5g | |
| MFCD00057220 | |
| 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole | |
| VNFPBHJOKIVQEB-UHFFFAOYSA-N | |
| 1-[(2-chlorophenyl)-diphenylmethyl]imidazole | |
| 2812 | |
| 344.84 |
Sikkerhed og håndtering
Produktidentifikator
Signalord
Farekategori
Faresætning
Sikkerhedssætning
Supplerende oplysninger
- Clotrimazole
Signalord
- Advarsel
Farekategori
- Akut toksicitet Kategori 4
- LANGTIDSFARE FOR VANDMILJØET Kronisk kategori 1
- AKUT FARE FOR VANDMILJØET Akut kategori 1
- Alvorlige øjenskader/øjenirritation Kategori 2
- Hudætsning/hudirritation Kategori 2
Faresætning
- H302-Farlig ved indtagelse.
- H315-Forårsager hudirritation.
- H319-Forårsager alvorlig øjenirritation.
- H400-Meget giftig for vandlevende organismer.
- H410-Meget giftig med langvarige virkninger for vandlevende organismer.
Sikkerhedssætning
- P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
- P301+P330+P331-I TILFÆLDE AF INDTAGELSE: Skyl munden. Fremkald IKKE opkastning.
- P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
- P305+P351+P338-VED KONTAKT MED ØJNENE: Skyl forsigtigt med vand i flere minutter. Fjern eventuelle kontaktlinser, hvis dette kan gøres let. Fortsæt skylning.
- P312-I tilfælde af ubehag, ring til en GIFTINFORMATION/læge/ .
Supplerende oplysninger
- MIXTURE LIST-Contain: Clotrimazole
Product Title
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