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Invitrogen™ Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488
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Artikelnummer. 10237304
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Mængde:
100 μg
Pakningsstørrelse:
Hver
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10237304 100 μg Hver
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Artikelnummer. 10237304 Leverandør Invitrogen™ Leverandørnr. 352588

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Beskrivelse

Mouse Monoclonal Antibody

Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Claudin 5
Applikationer ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon 4C3C2
Koncentration 0.5 mg/mL
Konjugeret Alexa Fluor 488
Formulering PBS with 4mg/mL BSA and 0.1% sodium azide; pH 7.4
Gene CLDN5
Genadgangsnr. O00501, O54942, Q9JKD6
Gene Alias AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Gensymboler CLDN5
Værtsarter Mouse
Immunogen Synthetic peptide derived from the mouse Claudin-5 protein.
Oprensningsmetode Protein A
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 12741, 65131, 7122
Målarter Human, Mouse, Rat
Indhold og opbevaring 4°C
Produkttype Antibody
Form Liquid
Isotype IgG1
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