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Invitrogen™ Claudin 1 Polyclonal Antibody (MH25)
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Artikelnummer. 10313553
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Mængde:
100 μg
Pakningsstørrelse:
100µg
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10313553 100 μg 100µg
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Artikelnummer. 10313553 Leverandør Invitrogen™ Leverandørnr. 717800

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Beskrivelse

Rabbit Polyclonal Antibody

This antibody reacts with the ~ 22 kDa Claudin-1 protein. Reactivity was confirmed by western blotting and immunofluorescence. Positive controls include MDCK cells (dog), Caco-2cells (human), mouse liver, rat liver, and rat kidney. NOTE: This antibody strongly cross reacts with the Claudin-3 protein. It has been observed in western blotting inhibition studies using Caco-2 cell lysates, that this antibody is inhibited by addition of Claudin-3 peptide. For a Claudin-1 specific antibody that does not cross-react with Claudin-3, please order Cat. No. 519000 (Rb x Claudin-1) instead.

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
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Tekniske data

Antigen Claudin 1
Applikationer ELISA, Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Klon MH25
Koncentration 0.25 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.1% sodium azide; pH 7.4
Gene CLDN1
Genadgangsnr. O88551, O95832, P56745
Gene Alias AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
Gensymboler CLDN1
Værtsarter Rabbit
Immunogen A synthetic peptide derived from the C-terminus of the human/mouse Claudin-1 protein.
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 12737, 608207, 65129, 9076
Målarter Human, Mouse, Rat, Canine
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG
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