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Invitrogen™ CHIA Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA563681
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Beskrivelse
Immunogen sequence: DTGSNAYLNV DYVMNYWKDN GAPAEKLIVG FPTYGHNFIL SNPSNTGIGA PTSGAGPAGP YAKESGIWAY YE Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.
CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
Tekniske data
| CHIA | |
| Polyclonal | |
| Unconjugated | |
| CHIA | |
| 2200003E03Rik; acidic chitinase; acidic mammalian chitinase; AMCASE; Chia; Chia1; CHIT2; chitinase, acidic; chitinase, acidic 1; eosinophil chemotactic cytokine; lung-specific protein TSA1902; small acid mammalian chitinase; TSA1902; YNL | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 27159 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9BZP6 | |
| CHIA | |
| Recombinant protein corresponding to Human CHIA. Recombinant protein control fragment (Product #RP-94208). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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