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Tocris Bioscience™ CGS 21680 hydrochloride
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Artikelnummer. 30001186
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Mængde:
10 mg
50 mg
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Artikelnummer. Mængde
30001186 10 mg
18094162 50 mg
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Artikelnummer. 30001186 Leverandør Tocris Bioscience™ Leverandørnr. 1063/10

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Beskrivelse

A2A agonist

CGS 21680 hydrochloride is a potent A2A adenosine receptor agonist (Ki = 27 nM, EC50 = 1.48-180 nM). CGS 21680 reduces venous resistance, increases heart rate and cardiac output in vivo. In an animal model of Huntington's disease, CGS21680 slows motor deterioration, prevents reduction in brain weight and reduces the size of mutant huntingtin aggregates and intranuclear inclusions. CGS21680 increases proliferation of neural progenitor cells, promotes survival of motoneurons and activates TrkB receptors. Also has anti-inflammatory effects in animal models of lung injury and reduces neurotoxicity induced by Kainate (Cat. No. 7065).
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 124431-80-7
Molekylær formel C23H30ClN7O6

Tekniske data

Kemisk navn eller materiale CGS 21680 hydrochloride
Mængde 10 mg
Formel vægt 535.99
Renhed >98%
Molekylvægt (g/mol) 535.986
Produkttitel
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