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Invitrogen™ CellSensor™ NFKB-bla HEK293T Cell Line
CellSensor™ NFKB-bla HEK293T cell line
Brand: Invitrogen™ K1664
Additional Details : Weight : 0.01000kg
Description
The CellSensor™ NFκB-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor kappa B (NFκB) response element. To obtain the cell line, the NFκB-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to isolate clones responsive to Tumor Necrosis Factor alpha (TNFα). The cell line has been validated for DMSO tolerance, stimulation time, substrate loading time, and EC50 concentration of TNFα. This cell line is responsive to TNFα and can be used to probe NFκB signaling pathways, including those that are involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease.Specifications
Cell-based beta lactamase reporter gene | |
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. | |
TNF alpha, NIK, TLR, I kappa B, IRAK, IKK, NF-kappa B pathway | |
Signaling Pathway |
Dividing Cells | |
CellSensor™ | |
CellSensor™ |
For Research Use Only. Not for use in diagnostic procedures.