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Invitrogen™ CDK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA580459

Product Code. 16367584

2630.00 DKK / 100µL

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Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CDK2/p33.

CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Specifications

Antigen	CDK2
Classification	Polyclonal
Conjugate	Unconjugated
Gene	CDK2
Gene Alias	A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Host Species	Rabbit
Purification Method	Antigen affinity chromatography, Protein A
Regulatory Status	RUO
Gene ID (Entrez)	1017
Content And Storage	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form	Liquid

Applications	ELISA, Immunoprecipitation, Western Blot
Concentration	1 mg/mL
Formulation	PBS with no preservative
Gene Accession No.	P24941
Gene Symbols	CDK2
Immunogen	Recombinant Human CDK2 protein (Met1-Leu298).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG

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Invitrogen™ CDK2 Polyclonal Antibody

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