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CD95 (APO-1/Fas) Mouse anti-Mouse, Super Bright 436, Clone: 15A7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Invitrogen 62-0951-82

Additional Details : Weight : 0.01000kg

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Product Code. 15855503

  • 2615.00 DKK / 100µg


Estimated Shipment date
from Supplier 04-06-2019
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Description

Description

When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (cat. SB-4400) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.
Specifications

Specifications

CD95 (APO-1/Fas)
Monoclonal
0.2 mg/mL
PBS with BSA and 0.09% sodium azide; pH 7.2
P25446
FAS
IgG1, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
14102
Flow Cytometry
15A7
Super Bright 436
Fas
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
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