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Invitrogen™ CD6 Recombinant Rabbit Monoclonal Antibody (002)
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Artikelnummer. 16394524
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Mængde:
100 μL
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16394524 100 μL
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Artikelnummer. 16394524 Leverandør Invitrogen™ Leverandørnr. MA531063

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Beskrivelse

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse CD6/Cluster of Differentiation 6.

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
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Tekniske data

Antigen CD6
Applikationer ELISA
Klassifikation Recombinant Monoclonal
Klon 002
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with no preservative
Gene CD6
Genadgangsnr. Q61003
Gene Alias Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
Gensymboler CD6
Værtsarter Rabbit
Immunogen Recombinant Mouse CD6/Cluster of Differentiation 6 Protein (Met1-Gly396).
Oprensningsmetode Protein A
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 12511
Målarter Mouse
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG
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