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BB700 Mouse Anti-Human CD56 Clone NCAM16.2 (NCAM16) (RUO)

Artikelnummer. 15835159
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Mængde:
100 Tests
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15835159 100 Tests
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Artikelnummer. 15835159 Leverandør BD Biosciences Leverandørnr. 566573

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Mouse monoclonal antibody that specifically binds to human CD56.

  • The NCAM16.2 monoclonal antibody specifically binds to human CD56.
  • It recognizes an extracellular immunoglobulin-like domain common to 120, 140, and 180 kDa forms of CD56, also known as the neural cell adhesion molecule (NCAM), NKH1 or MSK39.
  • The CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes.
  • It is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes. CD3+ CD56+ T lymphocytes comprise a unique subset of cytotoxic T lymphocytes that mediates non-major histocompatibility complex (MHC)-restricted cytotoxicity.
  • CD56 antigen density on NK lymphocytes increases upon cellular activation.
  • The CD56 antigen is involved in neuronal homotypic cell adhesion and cell differentiation during embryogenesis.
  • CD16+ CD56+ NK cells demonstrate reciprocal transfer of an activation state with dendritic cells.
  • The antibody was conjugated to BD Horizon BB700, which is part of the BD Horizon Brilliant™ Blue family of dyes.
  • It is a polymer-based tandem dye developed exclusively by BD Biosciences.
  • With an excitation max of 485 nm and an emission max of 693 nm, BD Horizon BB700 can be excited by the 488 nm laser and detected in a standard PerCP-Cy™5.5 set (eg, 695/40-nm filter).
  • This dye provides a much brighter alternative to PerCP-Cy5.5 with less cross laser excitation off the 405 nm and 355 nm lasers.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CD56 (NCAM-1)
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon NCAM16.2 (also known as NCAM 16)
Konjugeret Brilliant Blue 700 (BB700)
Værtsarter Mouse
Mængde 100 Tests
Regulatorisk status RUO
Primær eller sekundær Secondary
Testspecificitet CD56 (NCAM-1)
Målarter Human
Indhold og opbevaring Refrigerate (2 to 8°C)
Isotype IgG2b κ
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