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BB700 Mouse Anti-Human CD45RO, Clone UCHL1 (RUO)

Artikelnummer. 15805129
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100 Tests
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Artikelnummer. Mængde
15805129 100 Tests
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Artikelnummer. 15805129 Leverandør BD Biosciences Leverandørnr. 566521

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Beskrivelse

Mouse monoclonal antibody that specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen).

  • The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen).
  • CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways.
  • This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C.
  • CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells.
  • CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations.
  • CD45RO binds to CD22.
  • The antibody was conjugated to BD Horizon BB700, which is part of the BD Horizon Brilliant™ Blue family of dyes.
  • It is a polymer-based tandem dye developed exclusively by BD Biosciences.
  • With an excitation max of 485 nm and an emission max of 693 nm, BD Horizon BB700 can be excited by the 488 nm laser and detected in a standard PerCP-Cy™5.5 set (eg., 695/40-nm filter).
  • This dye provides a much brighter alternative to PerCP-Cy5.5 with less cross laser excitation off the 405 nm and 355 nm lasers.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CD45RO
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon UCHL1
Konjugeret Brilliant Blue 700 (BB700)
Værtsarter Mouse
Mængde 100 Tests
Regulatorisk status RUO
Primær eller sekundær Secondary
Testspecificitet CD45RO
Målarter Human
Indhold og opbevaring Refrigerate (2 to 8°C)
Isotype IgG2a κ
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