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CD45RA Monoclonal Antibody (HI100), Super Bright™ 702, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1394.00 DKK - 3235.00 DKK

Specifications

Antigen CD45RA
Clone HI100
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15855733
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Affymetrix eBioscience
67-0458-42
100 Tests
3235.00 DKK
Pack of 100
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15845733
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Affymetrix eBioscience
67-0458-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The HM48-1 monoclonal antibody reacts with the mouse CD48 antigen; also known as BCM1, Blast-1 (human), and OX-45 (rat). CD48, a member of the SLAM family and Ig superfamily, is a 45 kDa GPI-linked glycoprotein expressed on the majority of hematopoietic cells. Recent publications have reported differential expression of members of the SLAM family including CD48, CD150, and CD244 among functionally distinct bone marrow hematopoietic progenitors providing a useful tool for prediction of the primitiveness of hematopoietic progenitors based on the expression of these SLAM family members. Hematopoietic stem cells (HSC) are highly purified as CD150(+)CD244(-)CD48(-) cells while non-self-renewing multipotent hematopoietic progenitors (MPP) are CD244(+)CD150(-)CD48(-) and the most restricted progenitors are CD48(+)CD244(+)CD150(-). CD48 plays a critical role in adhesion and T cell activation. In the mouse, the primary counter-receptors for CD48 are CD2 and CD244. HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo. Applications Reported: This HM48-1 antibody has been reported for use in flow cytometric analysis.

CD45RA Monoclonal antibody specifically detects CD45RA in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD45RA
5 μL/Test
Monoclonal
Liquid
RUO
P08575
PTPRC
Primary
4° C, store in dark, DO NOT FREEZE!
PTPRC
HI100
Flow Cytometry
Super Bright 702
Mouse
Human
5788
IgG2b κ
Affinity chromatography
Antibody
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Documents

Documents

Product Certifications

For Research Use Only