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CD31 (PECAM-1) Mouse anti-Human, PE, Clone: WM-59 (WM59), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0319-42

Additional Details : Weight : 0.00050kg

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Product Code. 15297228

  • 1558.00 DKK / Each


In Stock 2
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Description

Description

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Specifications

Specifications

CD31 (PECAM-1)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P16284
CD31 antigen, CD31/EndoCAM, GPIIA′, PECA1, PECAM-1, CD31/EndoCAM, adhesion molecule, endoCAM, platelet endothelial cell adhesion molecule
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
WM-59 (WM59)
PE
PECAM1
Liquid
PECAM1
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
5175
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For Research Use Only.