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  6. Invitrogen™ CD31 Monoclonal Antibody (MBC78.2), FITC

Invitrogen™ CD31 Monoclonal Antibody (MBC78.2), FITC
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Artikelnummer. 10671244
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Mængde:
500 μL
2 mL
Pakningsstørrelse:
Hver
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10671244 500 μL Hver
10028632 2 mL Hver
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Artikelnummer. 10671244 Leverandør Invitrogen™ Leverandørnr. MHCD3101

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Beskrivelse

Mouse Monoclonal Antibody

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CD31
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon MBC78.2
Koncentration 0.2mg/mL
Konjugeret FITC
Oversigt CD31 Monoclonal Antibody, 0.5mL, 0.2mg/mL Concentration, MBC78.2 Clone, CD31 Antigen, Human CD31 Immunogen, Mouse Host, Human Species Reactivity, FITC Conjugate, IgG1 Isotype, PBS + BSA Storage Buffer, Used for Flow Cytometry
Fortynding Assay-dependent
Formulering PBS with 4mg/mL BSA and 0.1% sodium azide
Gene Pecam1
Genadgangsnr. P16284
Gene Alias C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Gensymboler Pecam1
Værtsarter Mouse
Immunogen Human CD31.
Oprensningsmetode Purified
Mængde 500 μL
Regulatorisk status ASR
Primær eller sekundær Primary
Gen-id (Entrez) 5175
Emballage 1 Each
Inkluderer 0.1% Sodium azide
Målarter Human
Indhold og opbevaring 4°C, store in dark
Produkttype Antibody
Form Liquid
Isotype IgG1
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