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CD30 (Reed-Sternberg Cell Marker) Ab-4 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD30 (Reed-Sternberg Cell Marker) Ab-4, Mouse Monoclonal Antibody.
Brand: Epredia MS-1857-P0
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Beskrivelse
CD30, a single chain glycoprotein, is synthesized as a 90 kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin's disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).Host Species: Mouse
Clone: HRS4
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: Extracellular domain
Immunogen: Recombinant extracellular domain of CD30 protein
Molecular Weight: 120 kDa (mature), 95 kDa (precursor)
Positive Control: Hodgkin's lymphoma
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Tekniske data
| CD30 Ab-4 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 100 μL | |
| Oncogenesis | |
| Human | |
| IgG1 |
| Immunohistochemistry (Paraffin) | |
| HRS4 | |
| Unconjugated | |
| Recombinant extracellular domain of CD30 protein | |
| IVD | |
| Primary | |
| Concentrated |
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